Searchable abstracts of presentations at key conferences in endocrinology

ea0037s19.1 | Metabolic dysfunction in PCOS | ECE2015

Genetic determinants of metabolic dysfunction in PCOS

Strauss Jerome , McAllister Jan

PCOS is a common disorder that is reported to affect 5–7% of women of reproductive age. Although there has been debate about the diagnostic criteria for PCOS, hyperandrogenemia/hyperandrogenism, not explained by other causes, is a hallmark of the disorder, and it is included as an essential element in all ‘consensus’ diagnostic schemes. Studies on cultures of human theca cells derived from normal and PCOS women have demonstrated that PCOS theca secretes greater ...